Product Name :
2,6-Dichlorobenzonitrile (CAS 1194-65-6)
Synonym :
Dichlobenil
Application :
CAS:
1194-65-6
Purity:
Molecular Weight:
172.01
Formula :
C7H3Cl2N
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
143-146° C (lit.)
SMILES:
C1=CC(=C(C(=C1)Cl)C#N)Cl
References:
:2,6-Dichlorobenzonitrile: a new herbicide. 1638744-20-3 site | KOOPMAN, H. and DAAMS, J. 1960. Nature. 186: 89-90. 882670-92-0 In stock PMID: 14410928The formation of 2,6-dichlorobenzonitrile from related compounds in plants. | Milborrow, BV. 1963. Biochem J. 87: 255-8. PMID: 16749003Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation. | Xie, F., et al. 2010. Toxicol Appl Pharmacol. 249: 101-6. PMID: 208408551,3-Dipolar cycloaddition of 2,6-dichlorobenzonitrile oxide to 2-methyl-N-confused porphyrin. Regio- and stereoselective synthesis and structural characterization of 2-aza-21-carbabacteriochlorin and resolution of 2-aza-21-carbachlorin enantiomers. | Li, X., et al. 2012. J Org Chem. 77: 2431-40. PMID: 22324296Disruption of cellulose synthesis by 2,6-dichlorobenzonitrile affects the structure of the cytoskeleton and cell wall construction in Arabidopsis. | Peng, L., et al. 2013. Plant Biol (Stuttg). 15: 405-14. PMID: 22759307Bioactivation of the nasal toxicant 2,6-dichlorobenzonitrile: an assessment of metabolic activity in human nasal mucosa and identification of indicators of exposure and potential toxicity. | Xie, F., et al. 2013. Chem Res Toxicol. 26: 388-98. PMID: 23360412Mechanisms of permanent loss of olfactory receptor neurons induced by the herbicide 2,6-dichlorobenzonitrile: effects on stem cells and noninvolvement of acute induction of the inflammatory cytokine IL-6. | Xie, F., et al. 2013. Toxicol Appl Pharmacol. 272: 598-607. PMID: 239211532, 6-Dichlorobenzonitrile causes multiple effects on pollen tube growth beyond altering cellulose synthesis in Pinus bungeana Zucc. | Hao, H., et al. 2013. PLoS One. 8: e76660. PMID: 24146903Early habituation of maize (Zea mays) suspension-cultured cells to 2,6-dichlorobenzonitrile is associated with the enhancement of antioxidant status. | Largo-Gosens, A., et al. 2016. Physiol Plant. 157: 193-204. PMID: 26612685Effect of 2, 6-Dichlorobenzonitrile on Amoebicidal Activity of Multipurpose Contact Lens Disinfecting Solutions. | Moon, EK., et al. 2018. Korean J Parasitol. 56: 491-494. PMID: 30419735Metabolism of 2,6-dichlorobenzonitrile, 2,6-dichlorothiobenzamide in rodents and goats. | Bakke, JE., et al. 1988. Xenobiotica. 18: 1063-75. PMID: 3067458Intermediary metabolism of 2,6-dichlorobenzonitrile (dichlobenil) in chickens and growth of chickens fed dichlobenil. | Davison, KL. and Bakke, JE. 1988. Xenobiotica. 18: 941-8. PMID: 3188573The comparative metabolism of 2,6-dichlorothiobenzamide (Prefix) and 2,6-dichlorobenzonitrile in the dog and rat. | Griffiths, MH., et al. 1966. Biochem J. 98: 770-81. PMID: 5911525Metabolic activation of 2,6-dichlorobenzonitrile, an olfactory-specific toxicant, by rat, rabbit, and human cytochromes P450. | Ding, X., et al. 1996. Mol Pharmacol. 49: 1113-21. PMID: 8649351Production of cellulose II by Acetobacter xylinum in the presence of 2,6-dichlorobenzonitrile. | Yu, X. and Atalla, RH. 1996. Int J Biol Macromol. 19: 145-6. PMID: 8842778
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