Product Name :
2-Amino-3-methoxybenzoic acid (CAS 3177-80-8)

Synonym :
3-Methoxyanthranilic acid

Application :

CAS:
3177-80-8

Purity:

Molecular Weight:
167.16

Formula :
C8H9NO3

Physical state:
Solid

solubility :

Shipping Condition :
Store at room temperature

Melting point:
169-170° C (lit.)

SMILES:
COC1=CC=CC(=C1N)C(=O)O

References:
:Synthesis and pharmacological testing of 1,2,3,4,10,14b-hexahydro-6-methoxy-2-methyldibenzo[c,f]pyrazino[1,2-a]azepin and its enantiomers in comparison with the two antidepressants mianserin and mirtazapine. | Wikström, HV., et al. 2002. J Med Chem. 45: 3280-5. Buy1239319-91-5 PMID: 12109911Substituent effects on the reactivity of benzo-1,2-dithiolan-3-one 1-oxides and their possible application to the synthesis of DNA-targeting drugs. | Sawwan, N., et al. 2005. J Org Chem. 70: 6968-71. PMID: 16095328Benzyne click chemistry with in situ generated aromatic azides. | Zhang, F. and Moses, JE. Formula of 1346809-61-7 2009. Org Lett. 11: 1587-90. PMID: 19267454The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis. | Wolff, H. and Bode, HB. 2018. PLoS One. 13: e0194297. PMID: 29596433Discovery and Optimization of 2-Amino-4-methylquinazoline Derivatives as Highly Potent Phosphatidylinositol 3-Kinase Inhibitors for Cancer Treatment. | Lin, S., et al. 2018. J Med Chem. 61: 6087-6109. PMID: 29927604A structural-chemical explanation of fungal laccase activity. | Mehra, R., et al. 2018. Sci Rep. 8: 17285. PMID: 30470810Novel textile dye obtained through transformation of 2-amino-3-methoxybenzoic acid by free and immobilised laccase from a Pleurotus ostreatus strain. | Wlizło, K., et al. 2020. Enzyme Microb Technol. 132: 109398. PMID: 3173197618F-labeled radiotracers for invivo imaging of DREADD with positron emission tomography. | Hu, F., et al. 2021. Eur J Med Chem. 213: 113047. PMID: 33280897Novel sulphonamide-bearing methoxyquinazolinone derivatives as anticancer and apoptosis inducers: synthesis, biological evaluation and in silico studies. | Alqahtani, AS., et al. 2022. J Enzyme Inhib Med Chem. 37: 86-99. PMID: 34894963Genome, transcriptome, and metabolome analyses provide new insights into the resource development in an edible fungus Dictyophora indusiata. | Duan, M., et al. 2023. Front Microbiol. 14: 1137159. PMID: 36846778Synthesis and recognition properties of alpha -D-glucose-based fluorescent crown ethers incorporating an acridine unit | Zsolt Rapi, Péter Bakó, György Keglevich, Péter Baranyai, Miklós Kubinyi & Olívia Varga. 2014. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 80: 253–261.Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties | Murat Bozdag a, Ahmed M. Alafeefy b, Fabrizio Carta a, Mariangela Ceruso a, Abdul-Malek S. Al-Tamimi c, Abdulla A. Al-Kahtani c d, Fatmah A.S. Alasmary d, Claudiu T. Supuran a. 2016. Bioorganic & Medicinal Chemistry. 24: 4100-4107.Dynamic changes in the chemical composition and metabolite profiles of drumstick (Moringa oleifera Lam.) leaf flour during fermentation | Honghui Shi a, Endian Yang c d e, Heyue Yang c d e, Xiaoling Huang c d e, Mengxia Zheng e, Xiaoyang Chen b c d e, Junjie Zhang c d e. 2022. LWT. 155.Effects of commercial sterilization on non-ginsenoside functional components in fresh ginseng pulps using widely targeted metabolomics | Junshun Zhang a, Zhiyi Ai a, Jian Wu b, Sitong Liu a, Yue Hu a, Yongzhe Liu a, Ping Tang a, Linlin Cui a, Xia Li a c, Chunhong Piao a c, Bo Nan a c, Yuhua Wang a c d e. 2023. LWT. 183.Chapter 6 – Benzene fused pyrimidine-based derivatives and their biological properties | Jeremy M. Kelm a, Hariprasad Aruri a, Prasanth R. Nyalapatla b, Navnath S. Gavande a. 20223. Fused Pyrimidine-Based Drug Discovery. 165-191.

Headquartered in New Jersey, USA, ChemScence is a global leading manufacturer and supplier of building blocks and fine research chemicals. We now have branches in Sweden and India. Our mission is to pave the way for drug discovery by providing the most innovative chemicals with the highest-level quality for a reasonable price.

Our Catalog Products

We deliver an extensive portfolio of products, including Building Blocks,Catalysts&Ligands,Synthetic Reagents,Material Science and ADC Linkers&Protac,.ChemScene now have over 600000 Building Blocks & Intermediates in our catalog and more than 70000 of them are in stock.

For details, please refer to the ChemScene website:https://www.chemscene.com