Product Name :
1,2-Bis-(tert-butyldimethylsilyl)hydrazine (CAS 10000-20-1)
Synonym :
Application :
1,2-Bis-(tert-butyldimethylsilyl)hydrazine is a hydrazine compound used to react with a carbonyl group producing a hydrazone
CAS:
10000-20-1
Purity:
98%
Molecular Weight:
260.57
Formula :
C12H32N2Si2
Physical state:
Liquid
solubility :
Soluble in chloroform, dichloromethane, and ethyl acetate. 1174020-44-0 web 212651-52-0 structure
Shipping Condition :
Store at 4° C
Melting point:
40.62° C (Predicted)
SMILES:
CC(C)(C)[Si](C)(C)NN[Si](C)(C)C(C)(C)C
References:
:Practical procedures for the preparation of N-tert-butyldimethylsilylhydrazones and their use in modified Wolff-Kishner reductions and in the synthesis of vinyl halides and gem-dihalides. | Furrow, ME. and Myers, AG. 2004. J Am Chem Soc. 126: 5436-45. PMID: 15113215A general procedure for the esterification of carboxylic acids with diazoalkanes generated in situ by the oxidation of N-tert-butyldimethylsilylhydrazones with (difluoroiodo)benzene. | Furrow, ME. and Myers, AG. 2004. J Am Chem Soc. 126: 12222-3. PMID: 15453728Total synthesis of the diazobenzofluorene antibiotic (−)-kinamycin C1. | Lei, X. and Porco, JA. 2006. J Am Chem Soc. 128: 14790-1. PMID: 17105273An enantioselective synthetic route toward second-generation light-driven rotary molecular motors. | Pijper, TC., et al. 2010. J Org Chem. 75: 825-38. PMID: 20055375Natural products containing a diazo group. | Nawrat, CC. and Moody, CJ. 2011. Nat Prod Rep. 28: 1426-44. PMID: 21589994Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists. | Selfridge, BR., et al. 2015. J Med Chem. 58: 5038-52. PMID: 26010811Nickel-catalyzed cross-coupling of aldehydes with aryl halides via hydrazone intermediates. | Tang, J., et al. 2018. Chem Commun (Camb). 54: 1750-1753. PMID: 29379918Synthetic and biosynthetic routes to nitrogen-nitrogen bonds. | He, HY., et al. 2022. Chem Soc Rev. 51: 2991-3046. PMID: 35311838Novel alpha6 preferring GABA-A receptor ligands based on loreclezole. | Simeone, X., et al. 2022. Eur J Med Chem. 244: 114780. PMID: 36279694Methyl Hydrazinocarboxylate as a Practical Alternative to Hydrazine in the Wolff–Kishner Reaction | Cranwell, P. B., Russell, A. T., & Smith, C. D. 2016. Synlett. 27(01): 131-135.The present and future synthetic strategies of structural modifications of sinomenine | Ng, J. P., Coghi, P., Law, B. Y. K., Liu, L., & Wong, V. K. W. 2020. Organic Chemistry Frontiers. 7(24): 4089-4107.
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