Product Name :
2,6-Dimethylaniline (CAS 87-62-7)
Synonym :
2,6-Xylidine
Application :
CAS:
87-62-7
Purity:
≥95%
Molecular Weight:
121.18
Formula :
(CH3)2C6H3NH2
Physical state:
Liquid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
10-12° C (lit.)
SMILES:
CC1=CC=CC(C)=C1N
References:
:Oxidation of 2,6-dimethylaniline by recombinant human cytochrome P450s and human liver microsomes. | Gan, J., et al. 2001. Chem Res Toxicol. 1-Cyclohexyl-2,2,2-trifluoroethan-1-ol Formula 14: 672-7. PMID: 11409937Analysis of the lidocaine metabolite 2,6-dimethylaniline in bovine and human milk. | Puente, NW. Fmoc-D-beta-indanylglycine site and Josephy, PD. 2001. J Anal Toxicol. 25: 711-5. PMID: 11765029The effect of deuterium and fluorine substitution upon the mutagenicity of N-hydroxy-2,6-dimethylaniline. | Matilde Marques, M., et al. 2002. Mutat Res. 506-507: 41-8. PMID: 12351143NTP Toxicology and Carcinogenesis Studies of 2,6-Xylidine (2,6-Dimethylaniline) (CAS No. 87-62-7) in Charles River CD Rats (Feed Studies). | ,. 1990. Natl Toxicol Program Tech Rep Ser. 278: 1-138. PMID: 12748701Chemical oxidation of 2,6-dimethylaniline by electrochemically generated Fenton′s reagent. | Masomboon, N., et al. 2010. J Hazard Mater. 176: 92-8. PMID: 19963316Chemical oxidation of 2,6-dimethylaniline in the fenton process. | Masomboon, N., et al. 2009. Environ Sci Technol. 43: 8629-34. PMID: 20028063Effect of carrier composition on 2,6-dimethylaniline degradation in aqueous solution by fluidized-bed Fenton process. | Ratanatamskul, C., et al. 2011. Environ Technol. 32: 1233-7. PMID: 21970165Elevated 4-aminobiphenyl and 2,6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers–The Shanghai Bladder Cancer Study. | Tao, L., et al. 2013. Cancer Epidemiol Biomarkers Prev. 22: 937-45. PMID: 23539508Covalent binding of [14C]-2,6-dimethylaniline to DNA of rat liver and ethmoid turbinate. | Short, CR., et al. 1989. J Toxicol Environ Health. 27: 85-94. PMID: 2724370The in vivo oxidative metabolism of 2,4- and 2,6-dimethylaniline in the dog and rat. | Short, CR., et al. 1989. Toxicology. 57: 45-58. PMID: 2749743Muscle-Type Nicotinic Receptor Modulation by 2,6-Dimethylaniline, a Molecule Resembling the Hydrophobic Moiety of Lidocaine. | Alberola-Die, A., et al. 2016. Front Mol Neurosci. 9: 127. PMID: 27932949Measurement of lidocaine and 2,6-dimethylaniline in minipig plasma, skin, and dermal tapes using UHPLC with electrospray MS/MS. | Li, Q., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1087-1088: 158-172. PMID: 29747144Effect of 2,6-xylidine (DMA) on secretion of biomarkers for inflammation and neurodevelopment by the placenta. | Arita, Y., et al. 2022. J Reprod Immunol. 149: 103458. PMID: 34952372Forward and reverse dosimetry for aniline and 2,6-dimethylaniline in humans extrapolated from humanized-liver mouse data using simplified physiologically based pharmacokinetic models. | Miura, T., et al. 2022. J Toxicol Sci. 47: 531-538. PMID: 364504972,6-Dimethylaniline (2,6-xylidine). | . 1993. IARC Monogr Eval Carcinog Risks Hum. 57: 323-35. PMID: 8207863
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