Product Name :
2,5-Dihydroxybenzoic acid (CAS 490-79-9)

Synonym :
Gentisic acid

Application :

CAS:
490-79-9

Purity:

Molecular Weight:
154.12

Formula :
C7H6O4

Physical state:
Solid

solubility :
Soluble in water, alcohol, ether, and methanol. Insoluble in chloroform.

Shipping Condition :
Store at room temperature

Melting point:
204-208° C (lit.)

SMILES:
OC(=O)C1=C(O)C=CC(O)=C1

References:
:2,5-Dihydroxybenzoic acid butylamine and other ionic liquid matrixes for enhanced MALDI-MS analysis of biomolecules. | Mank, M., et al. 1633667-60-3 Chemscene 2004. Anal Chem. 76: 2938-50. PMID: 15144208Assessment of antioxidant effect of 2,5-dihydroxybenzoic acid and vitamin a in brains of rats with induced hyperoxia. | Calderón Guzmán, D., et al. 1-(2-Hydroxy-5-iodophenyl)ethan-1-one Chemical name 2007. Neurochem Res. 32: 1036-40. PMID: 17401673A 2,5-dihydroxybenzoic acid/N,N-dimethylaniline matrix for the analysis of oligosaccharides by matrix-assisted laser desorption/ionization mass spectrometry. | Snovida, SI. and Perreault, H. 2007. Rapid Commun Mass Spectrom. 21: 3711-5. PMID: 17952888Mechanistic study of electrochemical oxidation of 2,5-dihydroxybenzoic acid and 3,4-dihydroxybenzaldehyde in the presence of 3-hydroxy-1H-phenalene-1-one. | Nematollahi, D. and Amani, A. 2008. Chem Pharm Bull (Tokyo). 56: 513-7. PMID: 18379100Comparative acute nephrotoxicity of salicylic acid, 2,3-dihydroxybenzoic acid, and 2,5-dihydroxybenzoic acid in young and middle aged Fischer 344 rats. | McMahon, TF., et al. 1991. Toxicology. 66: 297-311. PMID: 2011854Does decarboxylation make 2,5-dihydroxybenzoic acid special in matrix-assisted laser desorption/ionization? | Hsu, HC., et al. 2014. Rapid Commun Mass Spectrom. 28: 1082-8. PMID: 24711271Endogenous siderophore 2,5-dihydroxybenzoic acid deficiency promotes anemia and splenic iron overload in mice. | Liu, Z., et al. 2014. Mol Cell Biol. 34: 2533-46. PMID: 247776032,5-dihydroxybenzoic acid salts for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric lipid analysis: simplified spectra interpretation and insights into gas-phase fragmentation. | Jaskolla, TW., et al. 2014. Rapid Commun Mass Spectrom. 28: 1353-63. PMID: 247979462,5-Dihydroxybenzoic acid solution in MALDI-MS: ageing and use for mass calibration. | Teearu, A., et al. 2014. J Mass Spectrom. 49: 970-9. PMID: 25303386Magnetic core-shell iron(II,III) oxide@layered double oxide microspheres for removal of 2,5-dihydroxybenzoic acid from aqueous solutions. | Tang, S., et al. 2015. J Colloid Interface Sci. 437: 316-323. PMID: 25441367A uniform 2,5-dihydroxybenzoic acid layer as a matrix for MALDI-FTICR MS-based lipidomics. | Wei, Y., et al. 2015. Analyst. 140: 1298-305. PMID: 25568898A 2,5-Dihydroxybenzoic Acid-Gelatin Conjugate: The Synthesis, Antiviral Activity and Mechanism of Antiviral Action Against Two Alphaherpesviruses. | Lisov, A., et al. 2015. Viruses. 7: 5343-60. PMID: 26501311S5H/DMR6 Encodes a Salicylic Acid 5-Hydroxylase That Fine-Tunes Salicylic Acid Homeostasis. | Zhang, Y., et al. 2017. Plant Physiol. 175: 1082-1093. PMID: 288999632,3-Dihydroxybenzoic acid is a product of human aspirin metabolism. | Grootveld, M. and Halliwell, B. 1988. Biochem Pharmacol. 37: 271-80. PMID: 3342084Simultaneous determination of 5-aminosalicylic acid, acetyl-5-aminosalicylic acid and 2,5-dihydroxybenzoic acid in endoscopic intestinal biopsy samples in humans by high-performance liquid chromatography with electrochemical detection. | Palumbo, G., et al. 1995. J Pharm Biomed Anal. 14: 175-80. PMID: 8833980

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