Product Name :
2,5-Anhydro-D-mannitol-1,6-diphosphate Dibarium Salt (CAS 352000-03-4)

Synonym :

Application :
2,5-Anhydro-D-mannitol-1,6-diphosphate Dibarium Salt is an inhibitor of gluconeogenesis

CAS:
352000-03-4

Purity:

Molecular Weight:
630.70

Formula :
C6H14Ba2O13P2

Physical state:
Solid

solubility :
Soluble in water. 4-Bromo-6-chloropyridin-2-amine web 1445-55-2 Chemical name

Shipping Condition :
Store at -20° C

Melting point:
310° C (lit.)(dec.)

SMILES:
C([C@@H]1[C@H]([C@@H]([C@H](O1)COP(=O)([O-])[O-])O)O)OP(=O)([O-])[O-].O.O.[Ba+2].[Ba+2]

References:
:Nonhierarchical Flux Regulation Exposes the Fitness Burden Associated with Lactate Production in Synechocystis sp. PCC6803. | Du, W., et al. 2017. ACS Synth Biol. 6: 395-401. PMID: 27936615Inhibition of gluconeogenesis by 2,5-anhydro-D-mannitol in isolated rat hepatocytes. | Stevens, HC., et al. 1985. Biochim Biophys Acta. 845: 502-6. PMID: 3924119Periodate oxidations of enamines. I. Oxidation of adenosine 5′-monophosphate in the presence of methylamine. | Rammler, DH. 1971. Biochemistry. 10: 4699-705. PMID: 4334582On the mechanism of alkaline and neutral fructose 1, 6-diphosphatase: inhibition by substrate analogs at neutral pH. | De Maine, MM. and Benkovic, SJ. 1972. Arch Biochem Biophys. 152: 272-9. PMID: 4342110An examination of D-fructose 1,6-diphosphate and related sugar phosphates by fourier transform 31 P nuclear magnetic resonance spectroscopy. | Gray, GR. 1971. Biochemistry. 10: 4705-11. PMID: 5140187Inhibition of bovine hepatic fructose-1,6-diphosphatase by substrate analogs. | Marcus, CJ. 1976. J Biol Chem. 251: 2963-6. PMID: 5447An exploration of the active site of aldolase using structural analogs of fructose diphosphate. | Hartman, FC. and Barker, R. 1965. Biochemistry. 4: 1068-75. PMID: 5839994Mechanism of action of 2,5-anhydro-D-mannitol in hepatocytes. Effects of phosphorylated metabolites on enzymes of carbohydrate metabolism. | Riquelme, PT., et al. 1984. J Biol Chem. 259: 5115-23. PMID: 6325420Regulation of carbohydrate metabolism by 2,5-anhydro-D-mannitol. | Riquelme, PT., et al. 1983. Proc Natl Acad Sci U S A. 80: 4301-5. PMID: 6410389Differential hypoglycemic effect of 2,5-anhydro-D-mannitol, a putative gluconeogenesis inhibitor, in genetically diabetic (db/db) and streptozotocin-induced diabetic mice. | Kodama, H., et al. 1994. Jpn J Pharmacol. 66: 331-6. PMID: 7869620

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