.000 0.000 0.000 0.000 — 0.129 0.000 0.012 0.401 0.257 0.Results are presented as media ?SEM. Independent samples T-test and Mann hitney test for normalized and non-normalized samples, respectively. P adjusted for age and BMI (ANCOVA) when sufficient (when p0.05): for age when comparing female diabetic vs female control subjects; for BMI when comparing diabetic vs control (each for male and for female). BMI, body mass index; HbA1c, glycated hemoglobin; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-c, low-density lipoprotein cholesterol; Ox-LDL, oxidized low-density lipoprotein; TGs, triglycerides; Total-c, total cholesterol; WC, waist circumference.Mascarenhas-Melo et al. Cardiovascular Diabetology 2013, 12:61 http://cardiab/content/12/1/Page five ofTable two Information in the female diabetic population and age-matched controls: menopause influenceFemale manage group Parameters Age (years) BMI (Kg/m ) WC (cm) SBP (mmHg) DBP (mmHg) Glycemia (mmol/L) HbA1c ( ) Total-c (mmol/L) TGs (mmol/L) LDL-c (mmol/L) Ox-LDL (U/L) Non-HDL-c (mmol/L) PON1 activityFemale diabetic group P 0.6-Fluorobenzofuran-2-carboxylic acid In stock 000 0.472 0.575 0.004 0.175 0.038 — 0.364 0.455 0.514 0.044 0.390 Pre-M (n = eight) Post-M (n = 45) 43.88 ?1.29 29.43 ?2.44 one hundred.57 ?4.93 120.38 ?7.22 72.25 ?3.14 ten.80 ?1.65 9.03 ?1.08 4.68 ?0.44 1.51 ?0.31 two.71 ?0.35 34.83 ?.58 three.36 ?0.45 63.44 ?1.20 30.24 ?0.67 104.66 ?two.27 140.58 ?3.91 72.82 ?2.02 ten.67 ?0.64 9.23 ?0.30 4.93 ?0.16 2.08 ?0.17 2.69 ?0.15 31.89 ?1.61 three.60 ?0.17 498.39 ?35.22 P 0.000 0.578 0.081 0.048 0.519 0.832 0.477 0.725 0.467 0.997 0.993 0.781 0.Diabetic vs manage (P) Pre-menopausal Post- menopausal 0.349 0.221 0.103 0.187 0.027 0.000 — 0.313 0.066 0.164 0.897 0.236 0.527 0.345 0.013 0.000 0.113 0.000 0.000 — 0.090 0.003 0.007 0.339 0.243 0.Pre-M (n = 16) Post-M (n = 19) 45.63 ?1.12 26.93 ?1.21 91.38 ?2.86 132.69 ?five.62 84.25 ?three.20 four.92 ?0.10 — 5.08 ?0.16 1.02 ?0.08 3.21 ?0.17 29.13 ?1.76 3.68 ?0.17 415.66 ?26.78 62.37 ?1.35 27.21 ?0.85 93.06 ?2.75 153.56 ?four.61 90.89 ?two.52 5.31 ?0.14 — 5.48 ?0.21 1.13 ?0.ten 3.47 ?0.19 36.46 ?two.98 four.01 ?0.20 477.17?32.0.420 443.94 ?31.Benefits are presented as media ?SEM. Independent samples T-test and Mann hitney test for normalized and non-normalized samples, respectively.2-Ethynyl-1,1′-biphenyl In stock P adjusted for age and BMI (ANCOVA) when adequate (when p0.PMID:24883330 05): for age when comparing pre vs postmenopausal females (both in control and diabetic subjects); for BMI when comparing postmenopausal diabetic ladies vs postmenopausal control subjects. BMI, physique mass index; HbA1c, glycated hemoglobin; SBP, systolic blood pressure; DBP, diastolic blood stress; LDL-c, low-density lipoprotein cholesterol; Ox-LDL, oxidized low-density lipoprotein; TGs, triglycerides; Total-c, total cholesterol; WC, waist circumference.Values had been analyzed just after age and BMI adjustment when sufficient.Classical lipid profileAs previously talked about, diabetic individuals have been beneath antidyslipidemic therapy, which justify a few of the data obtained for the classic lipid profile. Hence, male diabetic individuals presented drastically reduce serum concentrations of Total-c, LDL-c, Ox-LDL-c and non-HDL-c when compared together with the male handle subjects. Identical profile was encountered in between female diabetic and manage people, with considerably reduce serum contents of LDL-c plus a trend to reduced Total-c, OxLDL-c and non-HDL-c for the female diabetic ladies (Table 1). Nonetheless, TGs and HDL-c concentrations showed a distinct profile, most probably as a result of anticipated lowe.